British Air Force Typhoon FGR4s have conducted a mission with France's air force in a joint strike against an underground arms cache in Syria operated by the Islamic State group (IS), according to the British defence ministry.
The facility, located using reconnaissance, was thought to be housing weapons and explosive materials, the statement said, and was positioned in mountainous terrain just above Palmyra in central Syria.
"The RAF jets employed Paveway IV guided bombs to strike a several approach shafts down to the facility... initial indications suggest the objective was successfully hit," the ministry announced.
There was no evidence of any civilian impact in the strike late on Saturday and each participating jet made a safe return, the defence officials confirmed.
The British jets were backed up by a Voyager tanker plane.
IS - also known as ISIS - enforced militant control over large swathes of Syria and Iraq before its territorial defeat in 2019.
"This operation demonstrates our UK leadership, and commitment to stand shoulder to shoulder with allied nations, to stamp out any revival of Daesh and their harmful and extremist ideologies in the region," UK Defence Secretary the Defence Secretary remarked.
UK warplanes have performed overwatch operations over Syrian airspace to "forestall any efforts to regroup" of the group following its defeat at the Baghuz confrontation in 2019, the MoD reported.
"I want to thank all the members of British forces involved in this operation for their professionalism and their courage," the Defence Secretary said. "They were among thousands of British personnel deployed over the festive period. This action, to eliminate militants who threaten our way of life, shows how British military are ready to step up, throughout the year, keeping Britain secure domestically and powerful internationally."
Last December, the US military conducted what it termed a "large-scale strike" on IS targets in Syria, following an assault resulted in the deaths of two US troops and a civilian interpreter in Palmyra.
The UN estimates Daesh still has an estimated 5,000 to 7,000 militants in Iraq and Syria.